Alpha Sigma Nu has chapters on 28 Jesuit campuses in the United States, Regis and Campion Colleges in Canada, and Sogang University, Seoul. Each chapter is responsible for the induction of new members every year. Activities vary from chapter to Chapter, led by student officers and an Alpha Sigma Nu Faculty Adviser. At Alpha Sigma Nu, a Chapter is not just another campus club. ΑΣΝ members are to be committed to bearing the name “Jesuit” in their lives as membership is an honor and a commitment. Alpha Sigma Nu members have a special connection with Jesuits, with Jesuit apostolic partners, and with Jesuit universities.

ΑΣΝ Chapters have long-standing traditions in such areas as retreats, tutoring services, honors convocations, leadership conferences, lecture series, outstanding teacher awards, reports to the university administration, and community service. Once inducted into ΑΣΝ, you have the opportunity to make a difference on your campus by running for a position of leadership within your Chapter.